Colorado State University Flint Animal Cancer Center
University / teaching hospital
10 current cancer treatment or research opportunities
About the Flint Animal Cancer Center
Colorado State's Flint Animal Cancer Center is one of the largest veterinary cancer programs in the world. For more than four decades it has combined treatment of pets with comparative cancer research, helping establish approaches now widely used in cancer surgery, chemotherapy and radiation care.
Cancer types currently listedGlioma, Leukemia, Oral Squamous Cell Carcinoma, Osteosarcoma, Soft Tissue Sarcoma, Urothelial Carcinoma
Where visits take placeFlint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
Current options at Colorado State University Flint Animal Cancer Center
Open an option to see who may qualify, locations, costs or coverage, contact details and the official source.
CAR T cell immunotherapy for treatment of metastatic osteosarcoma in dogs
Colorado State University Flint Animal Cancer Center · USA
Active - Recruiting
What is being offered: Appendicular OSA primary removed; measurable metastasis limited to lungs; dog ≥20 kg. No chemotherapy in preceding 2–3 weeks; no current steroids or immune-modifying medication. Blood collection about two weeks before treatment, preparatory chemotherapy, CAR T-cell infusion and daily oral medications; visits days 1, 3, 7, 14, 28, 60.
Who may qualify: Confirmed cancer diagnosis required; Metastatic; Active tumor required; Primary removed; Measurable lung metastases; Min weight kg: 20; Appendicular location; Prior surgery; Planned chemo
May not qualify if: Metastases outside lungs; Concurrent immunomodulatory drugs; Corticosteroids; Current steroids; Immunosuppressive
Costs / coverage: 🟡 Partially funded. Owners pay initial cancer diagnostics and examination fees at every study visit. Study treatment, CAR T-cell manufacture/infusion, study diagnostics and bloodwork are covered; screening assistance is available, with up to $2,000 for study-related side effects.
Contact: CSU Flint Animal Cancer Center Clinical Trials — (970) 297-4001; online clinical-trial consult form
Location
Flint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
CAR T-cell immunotherapy plus verdinexor for canine glioma
Colorado State University Veterinary Teaching Hospital · USA
Active - Recruiting
What is being offered: CSU protocol IACUC 5335 enrolls dogs over 10 lb with a presumptive or confirmed glioma. The protocol combines autologous engineered CAR T cells with oral verdinexor; radiation therapy is optional. Dogs may not have received prior chemotherapy or radiation. CSU lists recruitment through December 31, 2028; final neurologic and anesthesia eligibility requires study-team prescreening.
Who may qualify: Active tumor required; Planned radiation; Planned chemo; Min weight kg exclusive: 4.535923700100354
May not qualify if: Prior chemo; Prior radiation
Costs / coverage: 🟢 Fully funded. CSU states that CAR T-cell production and treatment, optional radiation therapy, MRIs, study examinations and bloodwork, and lifetime verdinexor chemotherapy are covered.
Novel immunotherapy for cats with oral squamous cell carcinoma
Colorado State University Flint Animal Cancer Center · USA
Actively recruiting — listed on CSU current clinical trials page
What is being offered: Four intratumoral immunotherapy injections under anesthesia every three weeks, with CT and biopsies to assess response. Study ends at day 84; all visits at CSU.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Accessible intratumoral target
May not qualify if: Immunosuppressive; Distant metastasis
Costs / coverage: 🟡 Partially funded. Screening support is available for CBC, chemistry, urine testing, lymph-node aspirates and chest radiographs. After acceptance, study examinations, blood tests, anesthesia, four immunotherapy injections, CT and biopsies are covered; up to $1,000 is available for study-related side effects. Owners pay cancer-diagnosis tests and any additional oncologist-recommended tests outside study coverage.
Contact: CSU Flint Animal Cancer Center Clinical Trials — (970) 297-4001; online clinical-trial consult form
Location
Flint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
3D-printed implant limb-sparing treatment for giant-breed dogs with primary bone tumors
Colorado State University Flint Animal Cancer Center · USA
Actively recruiting — listed on CSU current clinical trials page
What is being offered: Custom 3D-printed implant replaces affected distal-radius bone, followed by six chemotherapy treatments every three weeks and follow-up every two months up to 20 months. Frequent postoperative bandage changes are required; owner must agree to donate the limb after death.
Who may qualify: Active tumor required; Primary bone tumor; No metastasis; Appendicular location; Distal radius osteosarcoma; Giant breed or weight at least 40kg; Planned surgery; Planned chemo
May not qualify if: Immunosuppressive
Costs / coverage: 🟡 Partially funded. PET-CT/anesthesia, custom 3D-printed implant, surgery/hospitalization, six chemotherapy treatments and study follow-up imaging up to 20 months are covered, with up to $5,825 for surgical complications. Owners pay initial diagnosis/additional recommended tests, care outside CSU and complications beyond coverage.
Contact: CSU Flint Animal Cancer Center Clinical Trials — (970) 297-4001; online clinical-trial consult form
Location
Flint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
Lapatinib plus fractionated radiation therapy for canine transitional cell carcinoma
Colorado State University Flint Animal Cancer Center · USA
Actively recruiting — listed on CSU current clinical trials page
What is being offered: Daily oral lapatinib plus NSAID and 15 radiation fractions, with monthly follow-up for three months. Source timetable says 15 daily treatments within seven days of starting pills; this inconsistency requires study-team clarification rather than a guessed schedule.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Planned radiation; radiation washout: 42 days; chemotherapy washout: 14 days; Nsaid tolerant
Costs / coverage: 🟡 Partially funded. Lapatinib, recheck examinations, study bloodwork, urinary ultrasounds/sedation and $3,000 toward discounted radiation are covered; some side-effect funding is available. Owners pay initial examination/diagnosis including cystoscopy/biopsy, NSAID medication and radiation costs beyond study support.
Contact: CSU Flint Animal Cancer Center Clinical Trials — (970) 297-4001; online clinical-trial consult form
Location
Flint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
Engineered canine T cells with oral immunotherapy for soft tissue sarcoma
Colorado State University Flint Animal Cancer Center · USA
Actively recruiting — listed on CSU current clinical trials page
What is being offered: Autologous engineered CAR T-cell infusion with oral immunotherapy; tumor resection or repeat biopsy and follow-up
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Min weight kg: 11; chemotherapy washout: 14 days; Pretreatment biopsy; Planned chemo; radiation washout: 14 days
May not qualify if: Prior immunotherapy; Current chemo
Costs / coverage: Study support includes up to $3,200 in study-related treatment costs, $2,000 toward surgery or other treatment, oral immunotherapy medications excluding dispensing fees, and up to $500 for study-related side effects. Owners pay the initial exam/diagnostic testing and surgery costs beyond study support; screening-test assistance is available. Confirm the individual cost estimate with CSU.
Contact: CSU Flint Animal Cancer Center Clinical Trials — (970) 297-4001; online clinical-trial consult form
Location
Flint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
Intravenous carboplatin for pain control in canine appendicular osteosarcoma
Colorado State University Flint Animal Cancer Center · USA
Actively recruiting — listed on CSU current clinical trials page
What is being offered: Primary CSU current-trials page and study page list this study as enrolling as of 2026-09-09. A Veterinary Clinical Trials Registry profile says the study is on hold due to carboplatin shortage; per catalog policy, current institution study page is primary for enrollment status. Registry discrepancy retained for future recheck.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Appendicular location; Weight bearing; Planned chemo; Stable pain medication 7d; Bone medication washout 30d
May not qualify if: Prior chemo; Prior radiation; Bone metastasis
Costs / coverage: Study covers pre-enrollment CBC, chemistry, urinalysis, chest and limb radiographs and tumor aspirate/biopsy; after enrollment it covers one carboplatin treatment, study rechecks, repeat bloodwork and limb radiographs, plus initial anti-nausea/anti-diarrheal medications. Owners pay standard pain medication for the seven days before enrollment and additional chemotherapy side-effect care beyond the initial study-provided medication.
Contact: CSU Flint Animal Cancer Center Clinical Trials — (970) 297-4001; online clinical-trial consult form
Location
Flint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
Pilot clinical trial of trametinib treatment in dogs with acute myeloid leukemia (AML)
Colorado State University Flint Animal Cancer Center · USA
Actively recruiting — listed on CSU current clinical trials page
What is being offered: Pilot anti-cancer treatment study of trametinib in naturally occurring canine acute myeloid leukemia. Full protocol eligibility requires CSU prescreening.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Circulating leukemia cells
May not qualify if: Current chemo
Costs / coverage: 🟡 Partially funded. Study trametinib and prednisone, study-related diagnostic monitoring and sample shipping are covered. The source does not state that initial leukemia diagnosis or unrelated care is covered; confirm the individual owner estimate with CSU.
Contact: CSU Flint Animal Cancer Center Clinical Trials — (970) 297-4001; online clinical-trial consult form
Location
Flint Animal Cancer Center, 300 W Drake Rd, Fort Collins, CO 80523
Oral verdinexor chemotherapy for canine brain tumors
Colorado State University Veterinary Teaching Hospital · USA
Active - Recruiting
What is being offered: CSU protocol IACUC 6276 enrolls dogs weighing at least 10 kg (22 lb) with an MRI-confirmed brain tumor, particularly glioma, that are otherwise healthy. Dogs receive oral verdinexor twice weekly for six months and return on Days 1, 7, 21 and 42 and at Months 3 and 6. Prior chemotherapy or radiation excludes enrollment; final neurologic and anesthesia eligibility requires study-team prescreening.
Who may qualify: Active tumor required; Min weight kg: 10; Planned chemo
May not qualify if: Prior chemo; Prior radiation
Costs / coverage: 🟡 Partially funded. Owners pay a one-time $700 enrollment fee; CSU covers study chemotherapy, examinations, bloodwork and follow-up MRIs.
Single-fraction radiation therapy for canine transmissible venereal tumor
Colorado State University Veterinary Teaching Hospital · USA
Active - Recruiting
What is being offered: CSU protocol IACUC 7968 evaluates one modern radiation treatment for dogs with a confirmed, measurable and sampleable TVT lesion larger than 1 cm. Dogs must be suitable for anesthesia, have no advanced spread and have received no prior surgery, radiation or systemic chemotherapy for the tumor. Immunosuppressive drugs require a seven-day washout. Rechecks occur on Days 7 and 28.
Who may qualify: Confirmed cancer diagnosis required; Measurable; Active tumor required; Planned radiation; Min tumor cm exclusive: 1; Immunosuppressant washout 7d
May not qualify if: Prior surgery; Prior radiation; Prior systemic chemotherapy; Advanced metastatic disease
Costs / coverage: 🟡 Partially funded. The study covers pretreatment CBC/chemistry, indicated abdominal imaging, radiation planning and the single radiation treatment, plus Day 7 and Day 28 rechecks. If the tumor persists or progresses, a $1,000 credit is available toward standard chemotherapy.
A listing here does not mean every pet will qualify. Enrollment can change, and the study team makes the final decision after reviewing your pet’s diagnosis, records and previous treatment.
Have the pathology report, recent imaging and treatment history ready. Ask whether a referral is required, which visits must happen in person and what the study pays for before making travel plans.
