Michigan State University College of Veterinary Medicine
University / teaching hospital
4 current cancer treatment or research opportunities
About MSU veterinary oncology
Michigan State's oncology service treats dogs and cats while running a broad program of cancer research. Its teams study lymphoma, mast cell tumors, histiocytic sarcoma and other aggressive cancers, with laboratory scientists and hospital oncologists working together.
MSU oncology clinical trials →
Who the current listings are forDogs and cats
Cancer types currently listedHistiocytic Sarcoma, Lymphoma, Mammary Carcinoma, Mast Cell Tumor
Where visits take placeMichigan State University Veterinary Medical Center, 736 Wilson Rd, East Lansing, MI 48824
Current options at Michigan State University College of Veterinary Medicine
Open an option to see who may qualify, locations, costs or coverage, contact details and the official source.
CHOP versus LOPP for naïve canine T-cell lymphoma
Michigan State University · USA
Current — listed on MSU Oncology Clinical Trials
What is being offered: Randomized CHOP versus LOPP chemotherapy for treatment-naïve peripheral T-cell lymphoma, with genomic analysis. T-zone and cutaneous lymphoma are excluded. No prior chemotherapy or radiation; corticosteroids for up to 10 days may be allowed at the clinician’s discretion. Treatment lasts approximately 4–6 months with visits every 7–14 days, followed by monthly monitoring.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Planned chemo
May not qualify if: Current chemo; Prior local radiation; Indolent lymphoma
Costs / coverage: 🟡 Partially funded. Initial consultation, routine bloodwork and chemotherapy are owner-paid except the first doxorubicin (CHOP) or lomustine/CCNU (LOPP) dose, its administration and associated bloodwork. Recheck examination fees are covered. Approximately $250 for T-cell diagnosis performed at MSU is credited after study completion or progression; unrelated care remains owner-paid.
Contact: MSU Medical Oncology Team — (517) 353-5420; cvm.oncoinfo@msu.edu
Location
- Michigan State University Veterinary Medical Center, 736 Wilson Rd, East Lansing, MI 48824
Official study / enrollment information →
Quasiorganelle therapy for canine histiocytic sarcoma
Michigan State University Veterinary Medical Center · USA
Actively recruiting — current MSU clinical-trials page and August 24, 2026 recruitment announcement
What is being offered: First cohort receives weakened non-disease-causing Listeria-derived quasiorganelle therapy alone; second cohort receives quasiorganelle therapy including gene therapy. Up to 5 visible lesions are allowed with summed longest dimensions under 15 cm. Weekly treatment x4, then 2 weeks off, repeated for a total 16-week treatment period. While enrolled, dogs should not live with someone pregnant or planning pregnancy.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Measurable; Min weight kg: 20; Visible tumor; Max vcog performance status: 2
May not qualify if: Current chemo; Current steroids; Current radiation; Active wounds; Immunodeficiency; Immune mediated disease; Recent systemic antibiotics 14d; Recent immunosuppressants 14d; Recent prednisone 7d; Recent chemotherapy 14d; Recent radiation 30d
Costs / coverage: 🟢 Fully funded after enrollment. Trial-associated tests, quasiorganelle treatment, hospitalization, blood/fecal sampling, imaging and treatment of trial-related complications are covered; the initial evaluation is owner-paid.
Contact: MSU Medical Oncology Team — (517) 353-5420; cvm.oncoinfo@msu.edu
Location
- Michigan State University Veterinary Medical Center, 736 Wilson Rd, East Lansing, MI 48824
Official study / enrollment information →
Neoadjuvant corticosteroid response study for canine mast cell tumors
Michigan State University · USA
Current — listed on MSU Oncology Clinical Trials
What is being offered: Pre-surgical corticosteroid treatment for a confirmed cutaneous mast cell tumor on the trunk above the elbow or knee, measuring 2–6 cm in one dimension. Owners measure the tumor daily; MSU visits on days 7 and 14; surgery planned on day 14 ±1, potentially earlier for rapid shrinkage. Excludes metastasis, anticancer treatment including steroids within 7 days, inadequate NSAID washout (<5 days), and systemic conditions interfering with safe steroid use.
Who may qualify: Confirmed cancer diagnosis required; Measurable; No metastasis; Planned surgery; Min tumor cm: 2; Max tumor cm: 6; steroid washout days: 7 days; chemotherapy washout: 7 days
May not qualify if: Current chemo; Current steroids
Costs / coverage: 🟡 Partially funded. Up to 50% of surgical and histopathology fees are covered; trial-specific prednisone, diphenhydramine and famotidine/omeprazole and calipers are covered after enrollment. Initial consultation and eligibility diagnostics are owner-paid. Additional surgery under the same anesthesia is owner-paid.
Contact: MSU Medical Oncology Team — (517) 353-5420; cvm.oncoinfo@msu.edu
Location
- Michigan State University Veterinary Medical Center, 736 Wilson Rd, East Lansing, MI 48824
Official study / enrollment information →
Novel anticancer therapy for metastatic feline mammary carcinoma
Michigan State University · USA
Actively recruiting — listed on current MSU Oncology Clinical Trials
What is being offered: Investigational miR-10b-targeted therapeutic administered after baseline CT/MRI, repeated at two weeks and then with monthly imaging/treatment
Who may qualify: Confirmed cancer diagnosis required; Metastatic; Measurable
Costs / coverage: 🟡 Partially funded. Investigational miR-10b therapy and associated MRI/CT imaging are funded; unrelated diagnostics and treatment remain owner-paid.
Contact: MSU Medical Oncology — 517-353-5420; cvm.oncoinfo@msu.edu
Location
- Michigan State University Veterinary Medical Center, 736 Wilson Rd, East Lansing, MI 48824
Official study / enrollment information →
Before you contact the center
A listing here does not mean every pet will qualify. Enrollment can change, and the study team makes the final decision after reviewing your pet’s diagnosis, records and previous treatment.
Have the pathology report, recent imaging and treatment history ready. Ask whether a referral is required, which visits must happen in person and what the study pays for before making travel plans.
Check all options for your pet →
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