Ohio State University College of Veterinary Medicine
University / teaching hospital
4 current cancer treatment or research opportunities
About Ohio State comparative oncology
Ohio State has a large comparative oncology program linking its veterinary hospital with the university's human cancer center. Work by its veterinary researchers helped develop toceranib, sold as Palladia, the first cancer drug approved by the FDA specifically for dogs.
Ohio State oncology research →
Who the current listings are forDogs
Cancer types currently listedLymphoma, Oral Melanoma, Osteosarcoma, Soft Tissue Sarcoma
Where visits take placeThe Ohio State University Veterinary Medical Center, 601 Vernon L Tharp St, Columbus, OH 43210
Current options at Ohio State University College of Veterinary Medicine
Open an option to see who may qualify, locations, costs or coverage, contact details and the official source.
AI-guided biomechanical modeling and minimally invasive stabilization with SBRT for appendicular osteosarcoma
Ohio State University · USA
Current enrolling clinical trial — July 2026 list
What is being offered: Appendicular OSA treated with stereotactic body radiation; patient-specific biomechanical modeling identifies dogs who may benefit from intramedullary stabilization.
Who may qualify: No metastasis; Active tumor required; Appendicular location; Planned radiation; Planned chemo
Costs / coverage: 🟡 Partially funded. Study covers pre-operative limb CT and gait assessment, implant placement/anesthesia, implant, fluoroscopy, histopathology, specified limb radiographs and gait follow-up. A $1,000 direct payment is provided after study completion. SBRT and carboplatin chemotherapy are not covered.
Contact: Ohio State Blue Buffalo Veterinary Clinical Trials Office — CVM-ClinicalTrials@osu.edu
Location
- The Ohio State University Veterinary Medical Center, 601 Vernon L Tharp St, Columbus, OH 43210
Official study / enrollment information →
Anti-MIC antibody plus adoptive NK-cell therapy for canine soft tissue sarcoma
The Ohio State University Veterinary Medical Center · USA
Actively recruiting — confirmed on the institution’s current clinical-trials page
What is being offered: Localized confirmed STS treated with anti-MIC antibody and expanded natural-killer-cell infusion.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Localized
May not qualify if: Prior local radiation; Immunosuppressive
Costs / coverage: All trial-related procedures are covered and $700 compensation is provided upon trial completion.
Contact: Blue Buffalo Veterinary Clinical Trials Office — CVM-ClinicalTrials@osu.edu
Location
- The Ohio State University Veterinary Medical Center, 601 Vernon L Tharp St, Columbus, OH 43210
Official study / enrollment information →
Fully funded CAR-T cell therapy trial for canine B-cell lymphoma
LEAH Labs / University of Minnesota / Ohio State University / University of Missouri · USA
Missouri enrolling per current institutional protocol; Ohio State enrolling per sponsor with local slot to confirm; Minnesota on hold
What is being offered: One LEAH CAR-T protocol with site-specific cohorts. On October16 the current Missouri study-specific invitation and fresh Web read both explicitly confirm enrolling dogs with spontaneous CD20+ large-cell B-cell lymphoma; the older cached Missouri ON HOLD version is superseded. Missouri includes naive and relapsed patients, >10kg, clinically well, no primary GI or lung involvement, investigator bloodwork clearance, no Apoquel/mycophenolate/cyclosporine/azathioprine and at least72hours off prednisone. It combines lymphodepleting chemotherapy and xenogeneic CAR-T; at least seven visits over21days then longer follow-up. Minnesota current individual protocol remains On hold; its10-50kg and48hour rules must not be generalized to Missouri. Ohio remains enrolling per sponsor; its current institutional index does not name this protocol, so confirm the Ohio slot and local criteria before travel. Missouri-specific eligibility/funding do not establish Ohio or Minnesota terms.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Planned chemo
Costs / coverage: Missouri: study-related initial staging, treatment and rechecks covered; up to$4000 for adverse events and a$2000 stipend for future/additional VHC treatment upon completion. Sponsor describes Ohio enrollment as fully funded; confirm the current Ohio coverage and slot. Minnesota is on hold; its historical stipend/criteria are not generalized to other sites.
Contact: LEAH Labs — info@leahlabs.com; enrollment request form on the official site
Location
- The Ohio State University Veterinary Medical Center, 601 Vernon L Tharp St, Columbus, OH 43210
Official study / enrollment information →
Immunotherapy for canine oral melanoma
The Ohio State University Veterinary Medical Center · USA
Actively recruiting — confirmed on Ohio State's current clinical-trials page
What is being offered: Current Ohio State treatment study using intratumoral weakened LCMV followed by collection/expansion of tumor-infiltrating lymphocytes, with reinfusion if metastatic/progressive disease develops. Public criteria require localized confirmed oral melanoma accessible to injection/biopsy; a randomized control arm does not receive the virus injection but remains eligible for immune-cell collection/reinfusion if disease progresses.
Who may qualify: Confirmed cancer diagnosis required; Active tumor required; Measurable; Localized; Planned surgery
May not qualify if: Prior local radiation; Current immunosuppressive medications
Costs / coverage: Study covers tumor biopsy, two CT imaging sessions, trial-related blood work, viral reagent/injections, immune-cell collection/priming/reinfusion, plus an $800 post-trial incentive; confirm any remaining owner costs with Ohio State.
Contact: Blue Buffalo Veterinary Clinical Trials Office — CVM-ClinicalTrials@osu.edu
Location
- The Ohio State University Veterinary Medical Center, 601 Vernon L Tharp St, Columbus, OH 43210
Official study / enrollment information →
Before you contact the center
A listing here does not mean every pet will qualify. Enrollment can change, and the study team makes the final decision after reviewing your pet’s diagnosis, records and previous treatment.
Have the pathology report, recent imaging and treatment history ready. Ask whether a referral is required, which visits must happen in person and what the study pays for before making travel plans.
Check all options for your pet →
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