Vet Cancer Care Finder

Find oncology care / South Dakota

Veterinary oncology and cancer care in South Dakota

Local chemotherapy and tumor surgery for dogs and cats in South Dakota, with clinic contacts and published service limits. Check the proposed treatment and appointment before arranging a long trip.

23 physical locations · 2 physical locations list chemotherapy

Finding cancer care in South Dakota

Most locations below are general veterinary practices that publish tumor or mass-removal surgery. These services can be part of cancer care, but a surgery listing does not establish that the clinic can manage every tumor or has a board-certified veterinary oncologist. This review did not establish a resident board-certified medical oncologist, local radiation treatment or electrochemotherapy in South Dakota; it does not establish that none is available.

Upleash Veterinary Hospital in Sioux Falls and Dunes Animal Hospital in Dakota Dunes list local chemotherapy. Ask which veterinarian would manage your pet’s cancer, which drugs can be given there and whether an outside oncologist will help plan treatment. Upleash also lists tumor surgery; its optional oncology consultation does not establish an on-site medical oncologist. A chemotherapy listing does not confirm every protocol or an available appointment.

Visiting surgery at All Creatures Veterinary Hospital in Rapid City is coordinated through the hospital. Prairie View’s Highmore location publishes small-animal appointments and surgery about twice monthly. Confirm the proposed tumor operation and visit date; these schedules do not establish the same cancer service at every branch.

Local chemotherapy

Upleash Veterinary Hospital

208 W. 37th Street, Sioux Falls, SD, 57105

  • Local oncology care
  • Chemotherapy
  • Tumor surgery

Local chemotherapy and tumor/mass-removal surgery are offered. Advanced procedures may involve a visiting board-certified surgeon; confirm the assigned clinician and schedule. An optional oncology consultation does not establish an on-site medical oncologist.

605-271-3442Official clinic website

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Local cancer care and tumor surgery

Brandon Valley Veterinary Clinic

1000 E Redwood Blvd, Brandon, SD, 57005

  • Local oncology care
  • Tumor surgery

The small-animal service page explicitly lists mass removals, abdominal and reconstructive surgery. Confirm the procedure, treating veterinarian and schedule. Confirm case suitability and appointment availability directly with the clinic.

605-582-8575Official clinic website

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Heartland Veterinary Clinic

933 W Hwy 14 Bypass, Brookings, SD, 57006

  • Local oncology care
  • Tumor surgery

Owned small-animal page explicitly offers mass-removal surgery at the current Brookings practice. The old 312 Main Ave S address is not used. Confirm case suitability, assigned veterinarian and appointment availability directly with the clinic.

605-697-5252Official clinic website

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Cheyenne River Animal Hospital

202 10th Avenue, Edgemont, SD, 57735

  • Local oncology care
  • Tumor surgery

The hospital explicitly lists dog/cat mass removals. More advanced procedures and patients needing specialty-level care may be referred elsewhere; its regional ambulatory service does not establish mobile cancer surgery. Confirm case suitability and appointment availability directly with the clinic.

605-662-7838Official clinic website

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Pet Pawz Clinic

27154 427 Ave, Emery, SD, 57332

  • Local oncology care
  • Tumor surgery

The clinic explicitly lists in-office tumor and mass removal. Its welcome page accepts new clients. Confirm case suitability, assigned veterinarian and appointment availability directly with the clinic.

605-421-4855Official clinic website

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Dakota Large Animal Clinic

27199 475th Avenue, Harrisburg, SD, 57032

  • Local oncology care
  • Tumor surgery

Despite its name, the practice explicitly lists canine/feline care and small-animal mass removal. No cancer surgery in a mobile farm unit is inferred. Confirm case suitability and appointment availability directly with the clinic.

605-338-5558Official clinic website

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Prairie View Veterinary Clinic — Highmore

107 Iowa Ave S, Highmore, SD, 57345

  • Local oncology care
  • Tumor surgery

The current practice programme lists small-animal mass removals; its Highmore section says a doctor performs small-animal appointments and surgery about twice monthly. Call to confirm the tumor procedure, veterinarian and visit date. Other Prairie View branches are not cloned as separate confirmed tumor-surgery listings. Confirm case suitability and appointment availability directly with the clinic.

605-852-2494Official clinic website

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Montrose Veterinary Clinic

25633 451st Ave, Montrose, SD, 57048

  • Local oncology care
  • Tumor surgery

Owned dog and cat pages explicitly list mass-removal surgery and referral of complicated or risky cases. Clinical, team and contact details were reviewed through extended indexed owned-page bodies; direct retrieval failed. Confirm case suitability, assigned veterinarian and appointment availability directly with the clinic.

605-363-5353Official clinic website

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All Creatures Veterinary Hospital

1825 Clear View Ln, Rapid City, SD, 57702

  • Tumor surgery

Monthly visits by Kari Swanson for specialty surgery, including skin, abdominal and liver mass removal. Call the hospital for an initial consultation; the hospital coordinates records and surgery with the visiting surgeon.

605-342-0052Official clinic website

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Animal Clinic of Rapid City

1655 S Valley Dr, Rapid City, SD, 57703

  • Local oncology care
  • Tumor surgery

The branch lists mass removal and oncological soft tissue procedures. Emergency hours do not establish a scheduled surgery appointment. Confirm case suitability and appointment availability directly with the clinic.

605-342-1368Official clinic website

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Cook Veterinary Clinic

1727 E Anamosa St, Suite 100, Rapid City, SD, 57703

  • Local oncology care
  • Tumor surgery

The companion-animal surgical list includes tumor removal. Current published hours are Monday through Thursday; call to confirm case acceptance and operating veterinarian. Confirm case suitability and appointment availability directly with the clinic.

605-399-2665Official clinic website

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Dakota Hills Veterinary Clinic

1571 E Hwy 44, Rapid City, SD, 57703

  • Local oncology care
  • Tumor surgery

The clinic lists local mass removal. ELIAS names this clinic in its provider list, but current branch booking and ECI delivery remain unconfirmed; no immunotherapy service tag is added. Confirm case suitability and appointment availability directly with the clinic. Clinical details were reviewed through indexed copies of owned primary pages; direct retrieval remains restricted.

605-342-7498Official clinic website

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Meiners Animal Clinic

3500 W Chicago St, Rapid City, SD, 57702

  • Local oncology care
  • Tumor surgery

The companion-animal surgical list explicitly includes tumor removal. Confirm the scope of the proposed operation and appointment. Confirm case suitability and appointment availability directly with the clinic.

605-343-5089Official clinic website

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Mountain View Animal Hospital

1130 Jackson Blvd, Rapid City, SD, 57702

  • Local oncology care
  • Tumor surgery

The hospital explicitly lists tumor removal. Use its published contact-section telephone; the same page also displays a different texting/call prompt, so confirm the appointment before travelling. Confirm case suitability and appointment availability directly with the clinic. Clinical details were reviewed through indexed copies of owned primary pages; direct retrieval remains restricted.

605-343-8050Official clinic website

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All City Pet Care Veterinary Emergency Hospital

3508 S Minnesota Ave, Suite 102, Sioux Falls, SD, 57105

  • Local oncology care
  • Tumor surgery

The referral procedure list includes mass removal. Call this hospital for a consultation and arrange transfer of medical records; 24-hour emergency access is separate from scheduled surgery. Confirm case suitability and appointment availability directly with the clinic.

605-335-4004Official clinic website

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Best Care Pet Hospital

1102 E 10th St, Sioux Falls, SD, 57103

  • Local oncology care
  • Tumor surgery

Mass-removal surgery is listed. Current chemotherapy delivery is unconfirmed; the old recruitment advertisement names clinicians now at a different practice. Confirm case suitability and appointment availability directly with the clinic.

605-334-2412Official clinic website

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Faithful Friends Veterinary Care

3642 South Southeastern Avenue, Sioux Falls, SD, 57103

  • Local oncology care
  • Tumor surgery

The practice explicitly lists mass and tumor removals. Dale Animal Hospital is an earlier name, not a second current treatment location. Confirm case suitability and appointment availability directly with the clinic.

605-371-3791Official clinic website

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Heather Ridge Pet Hospital

5901 S Remington Place, Suite 100, Sioux Falls, SD, 57108

  • Local oncology care
  • Tumor surgery

The branch lists mass removals among its soft tissue surgical procedures. No chemotherapy, radiation or medical-oncology specialist is established. Confirm case suitability and appointment availability directly with the clinic.

605-371-1600Official clinic website

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Neighborhood Veterinary Care

208 S Main Street, Tripp, SD, 57376

  • Local oncology care
  • Tumor surgery

The practice explicitly lists mass removals among its soft tissue operations. Orthopedic or more specialized procedures may be referred elsewhere. Confirm case suitability and appointment availability directly with the clinic.

605-935-6820Official clinic website

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Apex Veterinary Center

320 4th St NE, Watertown, SD, 57201

  • Local oncology care
  • Tumor surgery

The practice lists mass removals and other soft tissue surgery. It explicitly does not perform orthopedic surgery; chemotherapy and oncology-specialist access are unconfirmed. Confirm case suitability and appointment availability directly with the clinic.

605-886-0898Official clinic website

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Glacial Lakes Veterinary Clinic

1200 9th Ave SE, Watertown, SD, 57201

  • Local oncology care
  • Tumor surgery

The practice lists laser surgical tumor removal. Surgical laser use is distinct from radiation therapy, electrochemotherapy and photodynamic treatment. Confirm case suitability and appointment availability directly with the clinic.

605-753-0876Official clinic website

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Lewis & Clark Veterinary Clinic — Yankton

504 East 2nd Street, Yankton, SD, 57078

  • Local oncology care
  • Tumor surgery

Mass-removal surgery is performed at the full-service Yankton facility. The Vermillion branch explicitly sends surgery to Yankton and is not another local surgical site. Confirm case suitability and appointment availability directly with the clinic.

605-260-5650Official clinic website

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Before booking surgery or chemotherapy

Ask whether the clinic treats your pet’s particular cancer, which veterinarian would see the case, whether a referral is required and which records to send. Confirm consultation, procedure and follow-up costs. For a mass removal, ask about the planned surgical margins, pathology and whether the case needs a specialist referral.

If a local veterinarian and an outside oncologist will share care, confirm who will provide the treatment plan, administer medication, review blood tests and handle problems between visits. Scheduled cancer care and emergency access are separate services.

For options beyond South Dakota, use the oncology care finder to compare neighboring states, including Minnesota, North Dakota, Nebraska, Iowa, Wyoming and Montana. The North Dakota guide and Wyoming guide describe their listed local services and limits. Oncology teleconsultations may offer specialist review; check whether each service accepts owners directly or requires a local veterinarian and whether it can advise on your case across state lines.

You can also search cancer clinical trials or read the cancer guides for dogs and cats. Trial eligibility and enrollment are separate from these clinic listings.

About this list: South Dakota coverage was reviewed on November 1, 2026. Individual record dates appear above. Page publication is not a new clinic verification. This is a selection of locations with published cancer-related services, not a complete census of every practice in the state. Specific services, branch allocation or primary-source information remain unconfirmed at other reviewed practices. An unlisted service is not proof that a clinic does not offer it.

Some records rely partly on indexed copies of clinic-authored pages where direct access was unavailable. At Heartland and Pet Pawz, the current assigned operating veterinarian requires confirmation; professional-license records do not establish present employment or appointment assignment.

Service information is compiled from clinic websites and professional public directories. Vet Cancer Care Finder does not independently verify clinicians, licenses, credentials or quality of care. Inclusion is not a recommendation. Confirm the clinician, service, cost and current availability directly with the clinic.